Gary A Weisman Selected Research

Nucleotides

4/2021	P2Y2 receptor antagonism resolves sialadenitis and improves salivary flow in a Sjögren's syndrome mouse model.
1/2021	P2Y receptors for extracellular nucleotides: Contributions to cancer progression and therapeutic implications.
6/2020	P2Y2 receptors mediate nucleotide-induced EGFR phosphorylation and stimulate proliferation and tumorigenesis of head and neck squamous cell carcinoma cell lines.
1/2020	P2 Receptors as Therapeutic Targets in the Salivary Gland: From Physiology to Dysfunction.
1/2019	Purinergic signaling in Alzheimer's disease.
4/2014	Loss of P2Y₂ nucleotide receptors enhances early pathology in the TgCRND8 mouse model of Alzheimer's disease.
10/2012	P2X7 receptor activation induces inflammatory responses in salivary gland epithelium.
9/2012	Neuroprotective roles of the P2Y(2) receptor.
8/2012	P2 receptors for extracellular nucleotides in the central nervous system: role of P2X7 and P2Y₂ receptor interactions in neuroinflammation.
6/2009	Interleukin-1beta enhances nucleotide-induced and alpha-secretase-dependent amyloid precursor protein processing in rat primary cortical neurons via up-regulation of the P2Y(2) receptor.

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Gary A Weisman Research Topics

Disease

13	Inflammation (Inflammations) 01/2022 - 01/2005
12	Neurodegenerative Diseases (Neurodegenerative Disease) 01/2019 - 10/2002
11	Alzheimer Disease (Alzheimer's Disease) 01/2019 - 05/2005
10	Astrocytoma (Pilocytic Astrocytoma) 06/2009 - 02/2003
8	Atherosclerosis 01/2009 - 11/2002
6	Hyperplasia 01/2016 - 11/2002
5	Neoplasms (Cancer) 01/2021 - 01/2019
4	Menkes Kinky Hair Syndrome (Menkes Disease) 11/2015 - 01/2012
3	Sialadenitis 04/2021 - 10/2012
3	Carcinogenesis 01/2021 - 01/2019
3	Xerostomia 12/2020 - 01/2019
2	Neoplasm Metastasis (Metastasis) 01/2021 - 01/2019
2	Head and Neck Neoplasms (Head and Neck Cancer) 01/2021 - 01/2019
2	Gliosis 01/2019 - 01/2005
2	Disease Progression 01/2019 - 06/2013
2	Wounds and Injuries (Trauma) 01/2017 - 10/2004
2	Seizures (Absence Seizure) 11/2015 - 06/2015
2	Spinal Muscular Atrophies of Childhood (Werdnig Hoffman Disease) 06/2015 - 01/2012
2	Neuroinflammatory Diseases 01/2015 - 08/2012
2	Type 2 Diabetes Mellitus (MODY) 06/2014 - 09/2012
2	Mitochondrial Diseases (Mitochondrial Disease) 02/2011 - 10/2005
2	Amyloid Plaque 09/2010 - 05/2005
2	Brain Injuries (Brain Injury) 11/2005 - 01/2005
2	Vascular System Injuries 07/2003 - 11/2002
1	Dacryocystitis (Dacryoadenitis) 01/2022
1	Thrombosis (Thrombus) 01/2021
1	Mucositis 12/2020
1	Squamous Cell Carcinoma of Head and Neck 06/2020
1	Mouth Neoplasms (Oral Cancer) 06/2020
1	Dental Caries (Decay, Dental) 01/2020
1	Ageusia (Hypogeusia) 01/2020
1	Autoimmune Diseases (Autoimmune Disease) 01/2020
1	Periodontitis 01/2020
1	Breast Neoplasms (Breast Cancer) 01/2019
1	Carcinoma (Carcinomatosis) 01/2019
1	Salmonella Infections (Salmonellosis) 01/2017
1	Infections 01/2017
1	Thyroid Diseases (Thyroid Disease) 01/2016
1	Ataxia (Dyssynergia) 11/2015
1	Intellectual Disability (Idiocy) 11/2015
1	Demyelinating Diseases (Demyelinating Disease) 11/2015
1	Muscular Atrophy (Muscle Atrophy) 06/2015
1	Failure to Thrive 06/2015
1	Muscle Hypotonia (Hypotonia) 06/2015
1	Fibrosis (Cirrhosis) 01/2015
1	Chondrocalcinosis (Pseudogout) 06/2014

Drug/Important Bio-Agent (IBA)

21	NucleotidesIBA 04/2021 - 11/2002
10	Purinergic P2Y2 ReceptorsIBA 04/2021 - 11/2002
8	Proteins (Proteins, Gene)FDA Link 01/2019 - 05/2005
7	GTP-Binding Proteins (G-Protein)IBA 04/2021 - 05/2005
7	CopperIBA 01/2019 - 09/2010
7	Amyloid (Amyloid Fibrils)IBA 01/2019 - 05/2005
6	Purinergic Receptors (Receptors, Purine)IBA 01/2022 - 06/2005
6	CytokinesIBA 01/2015 - 01/2005
5	Uridine Triphosphate (UTP)IBA 06/2020 - 11/2002
3	Indicators and Reagents (Reagents)IBA 06/2020 - 09/2006
3	Purinergic P2X7 ReceptorsIBA 01/2019 - 02/2003
3	Copper Transport ProteinsIBA 01/2017 - 01/2012
3	Amyloid beta-PeptidesIBA 03/2012 - 05/2005
3	Arachidonic Acid (Vitamin F)IBA 02/2011 - 10/2002
3	Messenger RNA (mRNA)IBA 10/2009 - 11/2002
2	Ion Channels (Ion Channel)IBA 01/2019 - 02/2003
2	Adenosine Triphosphate (ATP)IBA 01/2019 - 02/2003
2	P-type ATPasesIBA 01/2017 - 09/2010
2	N-Methylaspartate (NMDA)IBA 11/2015 - 02/2011
2	Peptides (Polypeptides)IBA 02/2011 - 09/2010
2	Phospholipases A2 (Phospholipase A2)IBA 06/2010 - 01/2005
2	Amyloid Precursor Protein Secretases (beta-Secretase)IBA 06/2009 - 05/2005
2	Vascular Cell Adhesion Molecule-1 (Vascular Cell Adhesion Molecule 1)IBA 01/2008 - 07/2003
2	UridineIBA 06/2005 - 11/2002
2	G-Protein-Coupled Receptors (Receptors, G Protein Coupled)IBA 01/2005 - 11/2002
1	Phenolsulfonphthalein (Phenol Red)IBA 01/2022
1	Mitogen-Activated Protein KinasesIBA 01/2021
1	Protein Kinases (Protein Kinase)IBA 01/2021
1	src-Family KinasesIBA 01/2021
1	NucleosidesIBA 01/2021
1	Extracellular Signal-Regulated MAP Kinases (Extracellular Signal Regulated Kinases)IBA 06/2020
1	Fura-2 (Fura 2)IBA 06/2020
1	ErbB Receptors (EGF Receptor)IBA 06/2020
1	AR-C118925IBA 06/2020
1	AlarminsIBA 01/2020
1	Protein-Lysine 6-Oxidase (Lysyl Oxidase)IBA 01/2019
1	Focal Adhesion Protein-Tyrosine KinasesIBA 01/2019
1	EnzymesIBA 01/2019
1	Purinergic P1 Receptors (Adenosine Receptor)IBA 01/2019
1	CD40 Ligand (CD40L)IBA 01/2018
1	AutoantibodiesIBA 01/2018
1	Carbachol (Carbastat)FDA Link 10/2017
1	3- (5- (2,3- dichlorophenyl)- 1H- tetrazol- 1- yl)methylpyridineIBA 10/2017
1	Sodium IodideIBA 01/2016
1	4- (5- benzo(1,3)dioxol- 5- yl- 4- pyridin- 2- yl- 1H- imidazol- 2- yl)benzamideIBA 01/2015
1	CollagenIBA 01/2015
1	4- (4- (3- (pyridin- 2- yl)- 1H- pyrazol- 4- yl)pyridin- 2- yl)- N- (tetrahydro- 2H- pyran- 4- yl)benzamideIBA 01/2015
1	Transforming Growth Factors (Transforming Growth Factor)IBA 01/2015
1	Fibronectins (Fibronectin)IBA 01/2015

Therapy/Procedure

4	Radiotherapy 01/2021 - 01/2019
1	Immunomodulation 01/2021
1	Therapeutics 06/2020
1	Denervation 06/2015
1	Ligation 01/2015